Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cross-serotypically conserved epitope recommendations for a universal T cell-based dengue vaccine

21 Sept 2020

Abstract excerpt

Dengue virus (DENV)-associated disease is a growing threat to public health across the globe. Co-circulating as four different serotypes, DENV poses a unique challenge for vaccine design as immunity to one serotype predisposes a person to severe and potentially lethal disease upon infection from other serotypes. Recent experimental studies suggest that an effective vaccine against DENV should elicit a strong T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32956362
DOI: 10.1371/journal.pntd.0008676

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cross-serotypically conserved epitope recommendations for a universal T cell-based dengue vaccinePMID 32956362Read ↗

Conserved epitopes with high HLA-I population coverage are targets of CD8+ T cells associated with high IFN-γ responses against all dengue virus serotypes.Semantic proximity Read ↗

Dengue antigenic relationships predict evolutionary dynamicsSemantic proximity Read ↗

Inferring Protective CD8+ T-Cell Epitopes for NS5 Protein of Four Serotypes of Dengue Virus Chinese Isolates Based on HLA-A, -B and -C Allelic Distribution: Implications for Epitope-Based Universal Vaccine Design.Semantic proximity Read ↗

Dengue genetic divergence generates within-serotype antigenic variation, but serotypes dominate evolutionary dynamicsSemantic proximity Read ↗

Highly conserved epitopes of DENV structural and non-structural proteins: Candidates for universal vaccine targetsSemantic proximity Read ↗

Immunoinformatic approach to design CTL epitope based chimeric vaccine targeting multiple serotypes of dengue virusSemantic proximity Read ↗

Conserved MHC Class I–Presented Dengue Virus Epitopes Identified by Immunoproteomics Analysis Are Targets for Cross-Serotype Reactive T-Cell ResponseSemantic proximity Read ↗

Conservation and Variability of Dengue Virus Proteins: Implications for Vaccine DesignSemantic proximity Read ↗

In silico design and evaluation of multi-epitope dengue virus vaccines: a promising approach to combat global dengue burdenSemantic proximity Read ↗

Immunoinformatics Aided Design and In-Vivo Validation of a Cross-Reactive Peptide Based Multi-Epitope Vaccine Targeting Multiple Serotypes of Dengue VirusSemantic proximity Read ↗

The Human CD8 <sup>+</sup> T Cell Responses Induced by a Live Attenuated Tetravalent Dengue Vaccine Are Directed against Highly Conserved EpitopesSemantic proximity Read ↗

A dengue monovalent vaccine with novel structure provides cross-protection against four serotypes of dengue virusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.