Article
Correlation between the number of segmental chromosome aberrations and the age at diagnosis of diploid neuroblastomas without MYCN amplification.
Journal of pediatric surgery - 1 Dec 2011
Souzaki Ryota, Tajiri Tatsuro, Teshiba Risa, Kinoshita Yoshiaki, Yosue Ryota, Kohashi Kenichi, Oda Yoshinao, Taguchi Tomoaki
Abstract excerpt
BACKGROUND: In neuroblastomas (NBs) without MYCN amplification, segmental chromosome aberrations SCAs such as 1p loss, 11q loss, and 17q gain have been suggested to be associated with the prognosis of the patients. We assessed the correlation between the number of SCAs and other biological factors in primary NBs samples. METHOD: The status of SCAs in 54 primary NBs samples was analyzed using the single-nucleotide...
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