Article
Single nucleotide polymorphism array analysis to predict clinical outcome in neuroblastoma patients.
Journal of pediatric surgery - 1 Dec 2006
Hiyama Eiso, Yamaoka Hiroaki, Kamimatsuse Arata, Onitake Yoshiyuki, Hiyama Keiko, Nishiyama Masahiko, Sueda Taijiro
Abstract excerpt
PURPOSE: Neuroblastoma (NB) is a heterogeneous tumor and demonstrates favorable or unfavorable outcomes. In Japan, a nationwide NB mass screening (MS) had been performed on 6-month-old infants for approximately 20 years, which might have detected almost all NB including regressing/maturing tumors. To clarify the heterogeneity of this tumor, we examined genetic alterations in the representative cases using...
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