Article
Genetic variants in IFIH1 play opposite roles in the pathogenesis of psoriasis and chronic periodontitis.
International journal of immunogenetics - 1 Apr 2012
Chen G, Zhou D, Zhang Z, Kan M, Zhang D, Hu X, Feng G, Liu Y, He L
Abstract excerpt
The IFIH1 gene is a key factor connecting environmental and genetic factors in the pathogenesis of immune-related diseases. We aimed to investigate whether it has effects on psoriasis, chronic periodontitis and skin test-positive penicillin allergy and to confirm whether these diseases have shared molecular mechanisms originating from shared genetics. Two common variants in IFIH1 were genotyped in 561 patients...
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