Article
Insulin receptor substrate-2 gene variants in subjects with metabolic syndrome: association with plasma monounsaturated and n-3 polyunsaturated fatty acid levels and insulin resistance.
Molecular nutrition & food research - 1 Feb 2012
Perez-Martinez Pablo, Delgado-Lista Javier, Garcia-Rios Antonio, Tierney Audrey C, Gulseth Hanne L, Williams Christine M, Karlström Brita, Kieć-Wilk Beata, Blaak Ellen E, Helal Olfa, Saris Wim H M, Defoort Catherine, Drevon Christian A, Lovegrove Julie A, Dembinska-Kieć Aldona, Riserus Ulf, Roche Helen M, Lopez-Miranda Jose
Abstract excerpt
SCOPE: Several insulin receptor substrate-2 (IRS-2) polymorphisms have been studied in relation to insulin resistance and type 2 diabetes. To examine whether the genetic variability at the IRS-2 gene locus was associated with the degree of insulin resistance and plasma fatty acid levels in metabolic syndrome (MetS) subjects. METHODS AND RESULTS: Insulin sensitivity, insulin secretion, glucose effectiveness,...
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