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Article

FADS cluster variants are associated with insulin sensitivity in children and adolescents with overweight and obesity.

European journal of clinical nutrition - 1 Dec 2022

Maguolo Alice, Zusi Chiara, Corradi Massimiliano, Emiliani Federica, Fornari Elena, Morandi Anita, Maffeis Claudio

Abstract excerpt

Changes in the desaturation activity of LC-PUFAs may influence insulin sensitivity by modulating the relative abundance of omega-3. The aim of this cross-sectional study was to assess the association between genetic variants of fatty acid desaturase cluster genes (FADS1, FADS2, FADS3) and insulin sensitivity in a cohort of children and adolescents with obesity. Anthropometric evaluation, lipid profile, glucose...

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Identifiers

PMID: 35906330
DOI: 10.1038/s41430-022-01187-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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