Article
Tyrosine phosphatases as a superfamily of tumor suppressors in colorectal cancer.
Acta biochimica Polonica - 1 Jan 2011
Laczmanska Izabela, Sasiadek Maria M
Abstract excerpt
Phosphorylation and dephosphorylation processes catalyzed by numerous kinases and phosphorylases are essential for cell homeostasis and may lead to disturbances in a variety of vital cellular pathways, such as cell proliferation and differentiation, and thus to complex diseases including cancer. As over 80 % of all oncogenes encode protein tyrosine kinases (PTKs), protein tyrosine phosphatases (PTPs), which can...
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