Article
SNPs and other features as they predispose to complex disease: genome-wide predictive analysis of a quantitative phenotype for hypertension.
PloS one - 1 Jan 2011
Won Joong-Ho, Ehret Georg, Chakravarti Aravinda, Olshen Richard A
Abstract excerpt
Though recently they have fallen into some disrepute, genome-wide association studies (GWAS) have been formulated and applied to understanding essential hypertension. The principal goal here is to use data gathered in a GWAS to gauge the extent to which SNPs and their interactions with other features can be combined to predict mean arterial blood pressure (MAP) in 3138 pre-menopausal and naturally post-menopausal...
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