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Article

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

Nature genetics - 1 Jan 2017

Hoffmann Thomas J, Ehret Georg B, Nandakumar Priyanka, Ranatunga Dilrini, Schaefer Catherine, Kwok Pui-Yan, Iribarren Carlos, Chakravarti Aravinda, Risch Neil

Abstract excerpt

Longitudinal electronic health records on 99,785 Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort individuals provided 1,342,814 systolic and diastolic blood pressure measurements for a genome-wide association study on long-term average systolic, diastolic, and pulse pressure. We identified 39 new loci among 75 genome-wide significant loci (P ≤ 5 × 10-8), with most replicating in the combined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27841878
DOI: 10.1038/ng.3715
PMCID: PMC5370207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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