Article
Semen quality parameters and embryo lethality in mice deficient for Trp53 protein.
Reproductive biology - 1 Nov 2011
Golas Aniela, Lech Tomasz, Janula Milosz, Bederska Dorota, Lenartowicz Malgorzata, Styrna Jozefa
Abstract excerpt
Trp53 is a protein which is able to control semen parameters in mice, but the extent of that control depends on the genetic background of the mouse strain. Males from C57BL/6Kw, 129/Sv, C57BL×129 -p53+/+ (wild type controls) and C57BL×129-p53-/- (mutants) strains were used in the study, and histology and light microscopy were applied to evaluate the influence of genetic background and Trp53 (p53) genotype on...
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