Article
Influence of p53 zygosity on select sperm parameters of the mouse.
Mutation research - 1 Jun 1999
Marty M S, Singh N P, Holsapple M P, Gollapudi B B
Abstract excerpt
The influence of p53 gene zygosity on select parameters of mouse sperm was investigated by employing knock-out animal models. The background incidence of sperm shape abnormalities, total sperm count, and DNA double strand breaks were determined in p53 nullizygous (-/-) and heterozygous (+/-) mice and these estimates were compared to the corresponding measures in p53 wild-type (+/+) and the inbred C57Bl6 mouse...
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