Article
Polygenic expression of teratozoospermia and normal fertility in B10.MOL-TEN1 mouse strain.
Congenital anomalies - 1 May 2015
Hirawatari Keitaro, Hanzawa Naoto, Kuwahara Maki, Aoyama Hiroaki, Miura Ikuo, Wakana Shigeharu, Gotoh Hideo
Abstract excerpt
Subfertility and infertility are two major reproductive health problems in human and domestic animals. The contribution of the genotype to these conditions is poorly understood. To examine the genetic basis of male subfertility, we analyzed its relationship to sperm morphology in B10.MOL-TEN1 mice, which shows high-frequencies (about 50%) of morphologically abnormal sperm. Drastic histological changes were also...
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