Article
Variations in exon 7 of the MSH2 gene and susceptibility to gastrointestinal cancer in a Chinese population.
Cancer genetics and cytogenetics - 15 Oct 2006
Fan Yimei, Liu Xiaorong, Zhang Huan, Dai Jin, Zhang Xiaomei, Zhu Ming, Gao Xiang, Wang Yaping
Abstract excerpt
Epidemiologic, structural, and bioinformatic analyses were used to evaluate variants in the MSH2 and MLH1 genes in 187 subjects with suspected hereditary gastrointestinal cancer in China. An increased frequency of variants was observed in exon 7 of the MSH2 gene; there was a statistical differenc...
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