Article
Transcriptional regulatory circuitries in the human pathogen Candida albicans involving sense--antisense interactions.
Genetics - 1 Feb 2012
Ahmad Ausaf, Kravets Anatoliy, Rustchenko Elena
Abstract excerpt
Candida albicans, a major human fungal pathogen, usually contains a diploid genome, but controls adaptation to a toxic alternative carbon source L-sorbose, by the reversible loss of one chromosome 5 (Ch5). We have previously identified multiple unique regions on Ch5 that repress the growth on sorbose. In one of the regions, the CSU51 gene determining the repressive property of the region was identified. We report...
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