Article
Pervasive transcription of the mitochondrial genome in Candida albicans is revealed in mutants lacking the mtEXO RNase complex.
RNA biology - 15 Oct 2021
Łabędzka-Dmoch Karolina, Kolondra Adam, Karpińska Magdalena A, Dębek Sonia, Grochowska Joanna, Grochowski Maciej, Piątkowski Jakub, Hoang Diu Bui Thi, Golik Paweł
Abstract excerpt
The mitochondrial genome of the pathogenic yeast Candida albicans displays a typical organization of several (eight) primary transcription units separated by noncoding regions. Presence of genes encoding Complex I subunits and the stability of its mtDNA sequence make it an attractive model to study organellar genome expression using transcriptomic approaches. The main activity responsible for RNA degradation in...
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