Article

The 5’ untranslated region of the <i>EFG1</i> transcript promotes its translation to regulate hyphal morphogenesis in <i>Candida albicans</i>

2018-05-23

Abstract excerpt

<h4>ABSTRACT</h4> Extensive 5’ untranslated regions (UTR) are a hallmark of transcripts determining hyphal morphogenesis in Candida albicans. The major transcripts of the EFG1 gene, which are responsible for cellular morphogenesis and metabolism, contain a 5’ UTR of up to 1170 nt. Deletion analyses of the 5’ UTR revealed a 218 nt sequence that is required for production of the Efg1 protein and its functions in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e770fd3d-cc93-53fe-bb74-a28dc1052163
DOI: 10.1101/328948

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The 5’ untranslated region of the <i>EFG1</i> transcript promotes its translation to regulate hyphal morphogenesis in <i>Candida albicans</i>DOI 10.1101/328948Read

The 5′ Untranslated Region of the EFG1 Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in Candida albicansSemantic proximity Read

A 5′ UTR ‐mediated translational efficiency mechanism inhibits the C andida albicans morphological transitionSemantic proximity Read

Filamentation in <i>Candida albicans</i> is modulated by adaptive translation of farnesol signalling genesSemantic proximity Read

Global translational landscape of the Candida albicans morphological transitionSemantic proximity Read

Generating genomic platforms to study <i>Candida albicans</i> pathogenesisSemantic proximity Read

Comprehensive mapping of the 5′ and 3′ untranslated regions of <i>Aspergillus fumigatus</i> reveals new insights into gene regulationSemantic proximity Read

Distinct Ire1-driven transcriptional responses control morphogenesis in <i>Candida albicans</i>Semantic proximity Read

Rfg1, a Protein Related to the <i>Saccharomyces cerevisiae</i> Hypoxic Regulator Rox1, Controls Filamentous Growth and Virulence in <i>Candida albicans</i>Semantic proximity Read

Induction of the<i>Candida albicans</i>Filamentous Growth Program by Relief of Transcriptional Repression: A Genome-wide AnalysisSemantic proximity Read

Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae.Semantic proximity Read

Ahr1 and Tup1 Contribute to the Transcriptional Control of Virulence-Associated Genes in Candida albicansSemantic proximity Read

Genome-wide RNA structural determination in <i>Candida</i> yeast pathogensSemantic proximity Read