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HLA-DRB1*15:01 and multiple sclerosis: a female association?

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 May 2012

Irizar Haritz, Muñoz-Culla Maider, Zuriarrain Olaia, Goyenechea Estibaliz, Castillo-Triviño Tamara, Prada Alvaro, Saenz-Cuesta Matias, De Juan Dolores, Lopez de Munain Adolfo, Olascoaga Javier, Otaegui David

Abstract excerpt

BACKGROUND: The association between multiple sclerosis (MS) and the HLA-DRB1*15:01 haplotype has been proven to be strong, but its molecular basis remains unclear. Vitamin D receptor (VDR) gene variants and sex have been proposed to modulate this association. OBJECTIVES: 1) Test the association of MS with *15:01 and VDR variants; 2) check whether VDR variants and/or sex modulate the risk conferred by *15:01; 3)...

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PMID: 22127897
DOI: 10.1177/1352458511426813

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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