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Article

Beyond Single Variants: A Pathway-Based Approach to Explore the Genetic Basis of Memory.

Molecular neurobiology - 15 Jan 2026

van Beek Daan, Kutmon Martina, de Kok Theo, Arts Ilja, Moerel Michelle, Adriaens Michiel

Abstract excerpt

Memory plays a crucial role in human cognitive processes and daily functioning. While memory has a genetic basis, identifying the specific genetic factors influencing memory performance has proven challenging. This challenge arises because memory is a complex trait, whose genetic architecture likely comprises an accumulation of many low-effect size common variants. Thus, study sample sizes are easily...

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PMID: 41535554
DOI: 10.1007/s12035-025-05582-1
PMCID: PMC12804229

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