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Article

Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.

Molecular carcinogenesis - 1 Sept 2012

Aytes Alvaro, Molleví David G, Martinez-Iniesta Maria, Nadal Marga, Vidal August, Morales Albert, Salazar Ramón, Capellà Gabriel, Villanueva Alberto

Abstract excerpt

Allelic imbalances at chromosome 4p have been largely documented in many different tumor types. In colorectal cancer, loss of heterozygosity (LOH) at 4p15 has been associated with tumor aggressiveness and poor patient outcome, however no target genes in the region have been identified to date. Since stromal interaction molecule 2 (STIM2) is located at 4p15.2 and has been proposed as a candidate gene for this...

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Source

Identifiers

PMID: 22125164
DOI: 10.1002/mc.20843

Genes

STIM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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