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Article

SMOC2, an intestinal stem cell marker, is an independent prognostic marker associated with better survival in colorectal cancers.

Scientific reports - 3 Sept 2020

Jang Bo Gun, Kim Hye Sung, Bae Jeong Mo, Kim Woo Ho, Kim Heung Up, Kang Gyeong Hoon

Abstract excerpt

We aimed to investigate the expression profile of SPARC-related modular calcium-binding protein 2 (SMOC2) during colorectal cancer (CRC) progression and assess its prognostic impact in CRC patients. In our study, we showed that SMOC2 transcript level was higher in CRC samples than in normal mucosa (P = 0.017); this level was not associated with candidate cancer stem cell markers (CD44, CD166, CD133, and CD24) or...

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Source

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Identifiers

PMID: 32884102
DOI: 10.1038/s41598-020-71643-1
PMCID: PMC7471277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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