Article
Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal cancer cells.
World journal of gastroenterology - 14 Oct 2016
Li Ying, Liu Yu-Hong, Hu Yu-Ying, Chen Lin, Li Jian-Ming
Abstract excerpt
AIM: To find the mechanisms by which special AT-rich sequence-binding protein 2 (SATB2) influences colorectal cancer (CRC) metastasis. METHODS: Cell growth assay, colony-forming assay, cell adhesion assay and cell migration assay were used to evaluate the biological characteristics of CRC cells with gain or loss of SATB2. Sphere formation assay was used to detect the self-renewal ability of CRC cells. The mRNA...
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