Article
Genetic variants in haem oxygenase-1 and endothelial nitric oxide synthase influence the extent and evolution of coronary artery atherosclerosis.
Folia biologica - 1 Jan 2011
Král A, Kovárník T, Králík L, Skalická H, Horák J, Mintz G S, Uhrová J, Sonka M, Wahle A, Downe R, Aschermann M, Martásek P, Linhart A
Abstract excerpt
The genetic basis for atherosclerosis development and progression is poorly characterized. We aimed to assess the relationship between endothelial nitric oxide synthase (ENOS) 894 G/T, haem oxygenase-1 (HO1) dinucleotide-length promoter polymorphisms and coronary artery atherosclerotic invol vement and its changes during statin therapy. Coronary angiography, intravascular ultrasound (IVUS), IVUS-derived virtual...
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