Article
Detection of epidermal growth factor receptor mutations in a few cancer cells from transbronchial cytologic specimens by reverse transcriptase-polymerase chain reaction.
Molecular diagnosis & therapy - 1 Dec 2011
Kanaji Nobuhiro, Bandoh Shuji, Ishii Tomoya, Kushida Yoshio, Haba Reiji, Kohno Kohoji, Dobashi Hiroaki, Ohnishi Hiroaki, Matsunaga Takuya
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) mutational status has the potential to be useful for determining prospective therapies in patients with non-small cell lung cancer (NSCLC) when analyzed in transbronchial cell specimens. The efficacy of RNA-based methods for the detection of EGFR mutations in transbronchial cell specimens has not been studied. Ultrafast Papanicolaou (UFP) staining is a method...
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