Article
EGFR mutational genotyping of liquid based cytology samples obtained via fine needle aspiration (FNA) at endobronchial ultrasound of non-small cell lung cancer (NSCLC).
Lung cancer (Amsterdam, Netherlands) - 1 Nov 2014
Reynolds Jordan P, Tubbs Raymond R, Minca Eugen C, MacNamara Stephen, Almeida Francisco A, Ma Patrick C, Pennell Nathan A, Cicenia Joseph C
Abstract excerpt
OBJECTIVES: Epidermal growth factor receptor (EGFR) gene mutation status should be determined in all patients with advanced, non-squamous non-small cell lung carcinoma (NSCLC) to guide targeted therapy with EGFR tyrosine kinase inhibitors. EGFR mutations are commonly tested by Sanger sequencing or allele specific polymerase chain reaction (ASPCR) on formalin-fixed paraffin-embedded (FFPE) samples including cell...
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