Article
Comparison of Confirmed Cytology Smears and Cell Blocks for Epidermal Growth Factor Receptor Mutation Testing in Non-Small Cell Lung Cancer.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2000
Liu Chia-Hsing, Chang Shu-Jyuan, Tsai Min-Jan, Yang Sheau-Fang
Abstract excerpt
INTRODUCTION: Various cytologic specimens have been used to diagnose epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer (NSCLC). However, insufficient samples and lengthy DNA extraction procedures have led to inconsistent diagnostic results. To reduce manipulation losses and improve DNA extraction quality, we provide an improved procedure for DNA extraction from smear samples...
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