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Article

Macrophage metabolism, phenotype, function, and therapy in hepatocellular carcinoma (HCC).

Journal of translational medicine - 15 Nov 2023

Huang Jingquan, Wu Qiulin, Geller David A, Yan Yihe

Abstract excerpt

The pivotal role of the tumor microenvironment (TME) in the initiation and advancement of hepatocellular carcinoma (HCC) is widely acknowledged, as it fosters the proliferation and metastasis of HCC cells. Within the intricate TME of HCC, tumor-associated macrophages (TAMs) represent a significant constituent of non-malignant cells. TAMs engage in direct communication with cancer cells in HCC, while also exerting...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37968714
DOI: 10.1186/s12967-023-04716-0
PMCID: PMC10652641

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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