Article
Characterization of NrnA homologs from Mycobacterium tuberculosis and Mycoplasma pneumoniae.
RNA (New York, N.Y.) - 1 Jan 2012
Postic Guillaume, Danchin Antoine, Mechold Undine
Abstract excerpt
Processive RNases are unable to degrade efficiently very short oligonucleotides, and they are complemented by specific enzymes, nanoRNases, that assist in this process. We previously identified NrnA (YtqI) from Bacillus subtilis as a bifunctional protein with the ability to degrade nanoRNA (RNA oligos ≤5 nucleotides) and to dephosphorylate 3'-phosphoadenosine 5'-phosphate (pAp) to AMP. While the former activity...
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