Article
Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study.
Journal of human genetics - 1 Jan 2012
Langberg Kurt A, Ma Lijun, Sharma Neeraj K, Hanis Craig L, Elbein Steven C, Hasstedt Sandra J, Das Swapan K
Abstract excerpt
Prior type 2 diabetes (T2D) genome-wide association studies (GWASs) have generated a list of well-replicated susceptibility loci in populations of European and Asian ancestry. To validate the trans-ethnic contribution of the single-nucleotide polymorphisms (SNPs) involved in these GWASs, we performed a family-based association analysis of 32 selected GWAS SNPs in a cohort of 1496 African-American (AA) subjects...
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