Article
A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila.
Molecular psychiatry - 1 Jan 2013
Allebrandt K V, Amin N, Müller-Myhsok B, Esko T, Teder-Laving M, Azevedo R V D M, Hayward C, van Mill J, Vogelzangs N, Green E W, Melville S A, Lichtner P, Wichmann H-E, Oostra B A, Janssens A C J W, Campbell H, Wilson J F, Hicks A A, Pramstaller P P, Dogas Z, Rudan I, Merrow M, Penninx B, Kyriacou C P, Metspalu A, van Duijn C M, Meitinger T, Roenneberg T
Abstract excerpt
Humans sleep approximately a third of their lifetime. The observation that individuals with either long or short sleep duration show associations with metabolic syndrome and psychiatric disorders suggests that the length of sleep is adaptive. Although sleep duration can be influenced by photoperiod (season) and phase of entrainment (chronotype), human familial sleep disorders indicate that there is a strong...
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