Article
Identifying pathways modulating sleep duration: from genomics to transcriptomics.
Scientific reports - 4 Jul 2017
Allebrandt Karla V, Teder-Laving Maris, Cusumano Paola, Frishman Goar, Levandovski Rosa, Ruepp Andreas, Hidalgo Maria P L, Costa Rodolfo, Metspalu Andres, Roenneberg Till, De Pittà Cristiano
Abstract excerpt
Recognizing that insights into the modulation of sleep duration can emerge by exploring the functional relationships among genes, we used this strategy to explore the genome-wide association results for this trait. We detected two major signalling pathways (ion channels and the ERBB signalling family of tyrosine kinases) that could be replicated across independent GWA studies meta-analyses. To investigate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
