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Article

Synthesis and evaluation of potential inhibitors of human and Escherichia coli histidine triad nucleotide binding proteins.

Bioorganic & medicinal chemistry letters - 1 Jan 2012

Bardaweel Sanaa K, Ghosh Brahma, Wagner Carston R

Abstract excerpt

Based on recent substrate specificity studies, a series of ribonucleotide based esters and carbamates were synthesized and screened as inhibitors of the phosphoramidases and acyl-AMP hydrolases, Escherichia coli Histidine Triad Nucleotide Binding Protein (ecHinT) and human Histidine Triad Nucleot...

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PMID: 22104145
DOI: 10.1016/j.bmcl.2011.10.082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22104145-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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