Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo.

PloS one - 1 Jan 2011

Bardaweel Sanaa, Ghosh Brahma, Chou Tsui-Fen, Sadowsky Michael J, Wagner Carston R

Abstract excerpt

Histidine triad nucleotide binding proteins (Hints) are highly conserved members of the histidine triad (HIT) protein superfamily. Hints comprise the most ancient branch of this superfamily and can be found in Archaea, Bacteria, and Eukaryota. Prokaryotic genomes, including a wide diversity of bo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Anhydride Hydrolases
Share to Alanine
Share to Biocatalysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biological Transport

Share to Escherichia coli K12

Share to Escherichia coli Proteins

Share to Operon

Share to Structure-Activity Relationship

Source

Open in PubMed Open full text

Identifiers

PMID: 21754980
DOI: 10.1371/journal.pone.0020897
PMCID: PMC3130732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21754980-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo.PMID 21754980Read ↗

Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli.Semantic proximity Read ↗

Impact of the C-terminal loop of histidine triad nucleotide binding protein1 (Hint1) on substrate specificity.Semantic proximity Read ↗

31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions.Semantic proximity Read ↗

Genetics and regulation of the major enzymes of alanine synthesis in Escherichia coli.Semantic proximity Read ↗

Mycobacterium smegmatis L-alanine dehydrogenase (Ald) is required for proficient utilization of alanine as a sole nitrogen source and sustained anaerobic growth.Semantic proximity Read ↗

Isolation of a mutant auxotrophic for L-alanine and identification of three major aminotransferases that synthesize L-alanine in Escherichia coli.Semantic proximity Read ↗

A TPR scaffold couples signal detection to OdhI phosphorylation in metabolic control by the protein kinase PknGSemantic proximity Read ↗

Semi-rational design of L-amino acid deaminase for production of pyruvate and D-alanine by Escherichia coli whole-cell biocatalyst.Semantic proximity Read ↗

Design and characterization of auxotrophy-based amino acid biosensors.Semantic proximity Read ↗

Alanine catabolism in Klebsiella aerogenes: molecular characterization of the dadAB operon and its regulation by the nitrogen assimilation control protein.Semantic proximity Read ↗

Mutant analysis shows that alanine racemases from Pseudomonas aeruginosa and Escherichia coli are dimeric.Semantic proximity Read ↗

In vivo continuous evolution via phenotypic sorting to alleviate metabolic bottlenecks in β-alanine production.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.