Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions.

The Journal of biological chemistry - 15 Apr 2005

Chou Tsui-Fen, Bieganowski Pawel, Shilinski Kara, Cheng Jilin, Brenner Charles, Wagner Carston R

Abstract excerpt

Eukaryotic cells encode AMP-lysine (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester) 5'-phosphoramidate) hydrolases related to the rabbit histidine triad nucleotide-binding protein 1 (Hint1) sequence. Bacterial and archaeal cells have Hint homologs annotated in a variety of ways, but the enzymes have not been characterized, nor have phenotypes been described due to loss of enzymatic activity. We developed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Monophosphate
Share to Guanosine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrolases

Share to Hydrolysis

Share to Magnetic Resonance Spectroscopy

Share to Models, Chemical

Share to Purines

Source

Open in PubMed Open full text

Identifiers

PMID: 15703176
DOI: 10.1074/jbc.M500434200
PMCID: PMC2556068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions.PMID 15703176Read ↗

Synthesis and evaluation of potential inhibitors of human and Escherichia coli histidine triad nucleotide binding proteins.Semantic proximity Read ↗

Evidence that human histidine triad nucleotide binding protein 3 (Hint3) is a distinct branch of the histidine triad (HIT) superfamily.Semantic proximity Read ↗

Impact of the C-terminal loop of histidine triad nucleotide binding protein1 (Hint1) on substrate specificity.Semantic proximity Read ↗

Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3.Semantic proximity Read ↗

E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo.Semantic proximity Read ↗

Identification of polyphosphate-binding proteins in <i>E. coli</i> uncovers targets involved in translation control and ribosome biogenesisSemantic proximity Read ↗

A study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase.Semantic proximity Read ↗

A regulatory role of the Bateman domain of IMP dehydrogenase in adenylate nucleotide biosynthesis.Semantic proximity Read ↗

Ubiquitous purine sensor modulates diverse signal transduction pathways in bacteriaSemantic proximity Read ↗

A TPR scaffold couples signal detection to OdhI phosphorylation in metabolic control by the protein kinase PknGSemantic proximity Read ↗

Complete deficiency of 5'-nucleotidase activity in Escherichia coli leads to loss of growth on purine nucleotides but not of their excretion.Semantic proximity Read ↗

Ubiquitous purine sensor modulates diverse signal transduction pathways in bacteriaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.