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Article

Evaluation of multiple risk-associated single nucleotide polymorphisms versus prostate-specific antigen at baseline to predict prostate cancer in unscreened men.

European urology - 1 Mar 2012

Klein Robert J, Hallden Christer, Gupta Amit, Savage Caroline J, Dahlin Anders, Bjartell Anders, Manjer Jonas, Scardino Peter T, Ulmert David, Wallström Peter, Vickers Andrew J, Lilja Hans

Abstract excerpt

BACKGROUND: Although case-control studies have identified numerous single nucleotide polymorphisms (SNPs) associated with prostate cancer, the clinical role of these SNPs remains unclear. OBJECTIVE: Evaluate previously identified SNPs for association with prostate cancer and accuracy in predicting prostate cancer in a large prospective population-based cohort of unscreened men. DESIGN, SETTING, AND PARTICIPANTS:...

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Identifiers

PMID: 22101116
DOI: 10.1016/j.eururo.2011.10.047
PMCID: PMC3269546

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