Article
The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1.
The EMBO journal - 1 Oct 1990
Bosselut R, Duvall J F, Gégonne A, Bailly M, Hémar A, Brady J, Ghysdael J
Abstract excerpt
The c-ets-1 proto-oncogene and the related c-ets-2 gene encode related nuclear chromatin-associated proteins which bind DNA in vitro. To investigate the possibility that Ets1 and Ets2 are transcriptional activators, we analyzed the ability of these proteins to trans-activate promoter/enhancer seq...
Topics
- Animals
- Base Sequence
- Cell Line
- Chloramphenicol O-Acetyltransferase
- Chromosome Deletion
- HeLa Cells
- Human T-lymphotropic virus 1
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Plasmids
- Protein-Tyrosine Kinases
- Proto-Oncogene Mas