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Article

Interaction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression.

Journal of the National Cancer Institute - 17 Dec 2003

Twizere Jean-Claude, Kruys Véronique, Lefèbvre Laurent, Vanderplasschen Alain, Collete Delphine, Debacq Christophe, Lai Wi S, Jauniaux Jean-Claude, Bernstein Lori R, Semmes O John, Burny Arsène, Blackshear Perry J, Kettmann Richard, Willems Luc

Abstract excerpt

BACKGROUND: The Tax oncoproteins are transcriptional regulators of viral expression involved in pathogenesis induced by complex leukemogenic retroviruses (or delta-retroviruses, i.e., primate T-cell leukemia viruses and bovine leukemia virus). To better understand the molecular pathways leading to cell transformation, we aimed to identify cellular proteins interacting with Tax. METHODS: We used a yeast two-hybrid...

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PMID: 14679154
DOI: 10.1093/jnci/djg118

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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