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Article

Human T-cell leukemia virus type 1 Tax relieves repression of proliferating cell nuclear antigen gene expression.

Journal of virology - 1 Dec 2008

Edwards Dustin C, Marriott Susan J

Abstract excerpt

Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia. The transforming ability of Tax, the viral oncoprotein, is believed to depend on interactions with cell cycle regulators and on transactivation of genes that control cellular proliferation, including proliferating cell nuclear antigen (PCNA), a cofactor associated with DNA replication and repair. Tax associates with...

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Share to Cell Line
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Proliferating Cell Nuclear Antigen

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Source

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Identifiers

PMID: 18799587
DOI: 10.1128/JVI.00356-08
PMCID: PMC2583679

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human T-cell leukemia virus type 1 Tax relieves repression of proliferating cell nuclear antigen gene expression.PMID 18799587Read ↗

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