Article
Atorvastatin and hormone therapy effects on APOE mRNA expression in hypercholesterolemic postmenopausal women.
The Journal of steroid biochemistry and molecular biology - 1 Feb 2012
Issa Mustafa H, Cerda Alvaro, Genvigir Fabiana D V, Cavalli Selma A, Bertolami Marcelo C, Faludi Andre A, Hirata Mario H, Hirata Rosario D C
Abstract excerpt
Menopause is associated with changes in lipid levels resulting in increased risk of atherosclerosis and cardiovascular events. Hormone therapy (HT) and atorvastatin have been used to improve lipid profile in postmenopausal women. Effects of HT, atorvastatin and APOE polymorphisms on serum lipids and APOE and LXRA expression were evaluated in 87 hypercholesterolemic postmenopausal women, randomly selected for...
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