Article
Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin.
Lipids in health and disease - 10 Nov 2011
Cerda Alvaro, Genvigir Fabiana D V, Willrich Maria A V, Arazi Simone S, Bernik Marcia M S, Dorea Egidio L, Bertolami Marcelo C, Faludi Andre A, Hirata Mario H, Hirata Rosario D C
Abstract excerpt
BACKGROUND: Apolipoprotein E (apoE) is a key component of the lipid metabolism. Polymorphisms at the apoE gene (APOE) have been associated with cardiovascular disease, lipid levels and lipid-lowering response to statins. We evaluated the effects on APOE expression of hypercholesterolemia, APOE ε2/ε3/ε4 genotypes and atorvastatin treatment in Brazilian individuals. The relationship of APOE genotypes and plasma...
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