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Article

Association of APOE polymorphisms with lipid-lowering efficacy of statins in atherosclerotic cardiovascular diseases.

Annals of the Academy of Medicine, Singapore - 1 Jun 2021

Wang Yuexi, Du Xiaohong, Zhao Ruifen, Niu Juan, Wang Haixu, Li Jing

Abstract excerpt

INTRODUCTION: The apolipoprotein E (APOE) gene is a promising candidate for the diagnosis of hyperlipoproteinaemia and atherosclerosis. Polymorphisms in APOE have been reported to result in differential efficacies of statin drugs in atherosclerotic cardiovascular disease. METHODS: We classified the APOE genotypes of 225 patients treated with atorvastatin, and analysed the relation between genotypes and serum...

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PMID: 34195754

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