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Article

Ten novel mutations in the erythroid transcription factor KLF1 gene associated with increased fetal hemoglobin levels in adults.

Haematologica - 1 Mar 2012

Gallienne Alice E, Dréau Hélène M P, Schuh Anna, Old John M, Henderson Shirley

Abstract excerpt

We investigated whether mutations in the KLF1 gene are associated with increased Hb F levels in ethnically diverse patients referred to our laboratory for hemoglobinopathy investigation. Functionally effective KLF1 mutations were identified in 11 out of 131 adult samples with an elevated Hb F lev...

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Share to Aged, 80 and over
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Share to Fetal Hemoglobin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kruppel-Like Transcription Factors

Source

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Identifiers

PMID: 22102705
DOI: 10.3324/haematol.2011.055442
PMCID: PMC3291586

Genes

KLF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22102705-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Ten novel mutations in the erythroid transcription factor KLF1 gene associated with increased fetal hemoglobin levels in adults.PMID 22102705Read ↗

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