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Article

Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 16 Nov 2011

Yamasaki Tokiwa, Kawasaki Hiroshi, Arakawa Satoko, Shimizu Kimiko, Shimizu Shigeomi, Reiner Orly, Okano Hideyuki, Nishina Sachiko, Azuma Noriyuki, Penninger Josef M, Katada Toshiaki, Nishina Hiroshi

Abstract excerpt

The c-Jun NH(2)-terminal protein kinase (JNK), which belongs to the mitogen-activated protein kinase family, plays important roles in a broad range of physiological processes. JNK is controlled by two upstream regulators, mitogen-activated protein kinase kinase (MKK) 7 and MKK4. To elucidate the physiological functions of MKK7, we used Nestin-Cre to generate a novel mouse model in which the mkk7 gene was...

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Identifiers

PMID: 22090513
DOI: 10.1523/JNEUROSCI.1111-11.2011
PMCID: PMC6633308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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