Article
Role of dual leucine zipper-bearing kinase (DLK/MUK/ZPK) in axonal growth.
Neuroscience research - 1 Jan 2010
Eto Kaoru, Kawauchi Takeshi, Osawa Makiko, Tabata Hidenori, Nakajima Kazunori
Abstract excerpt
In developing cerebral cortices, post-mitotic neurons migrate toward the pial surface, elongating their axons concurrently. It has been reported that targeted-deletion of the dual leucine zipper-bearing kinase (DLK)/mitogen-activated protein kinase upstream protein kinase (MUK)/leucine-zipper protein kinase (ZPK) gene, which encodes a MAP kinase kinase kinase (MAPKKK) for c-Jun N-terminal kinase (JNK), leads to a...
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