Article
In vivo fate mapping identifies mesenchymal progenitor cells.
Stem cells (Dayton, Ohio) - 1 Feb 2012
Grcevic Danka, Pejda Slavica, Matthews Brya G, Repic Dario, Wang Liping, Li Haitao, Kronenberg Mark S, Jiang Xi, Maye Peter, Adams Douglas J, Rowe David W, Aguila Hector L, Kalajzic Ivo
Abstract excerpt
Adult mesenchymal progenitor cells have enormous potential for use in regenerative medicine. However, the true identity of the progenitors in vivo and their progeny has not been precisely defined. We hypothesize that cells expressing a smooth muscle α-actin promoter (αSMA)-directed Cre transgene represent mesenchymal progenitors of adult bone tissue. By combining complementary colors in combination with...
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