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Article

Regional specialization and fate specification of bone stromal cells in skeletal development

1 Jul 2021

Abstract excerpt

Bone stroma contributes to the regulation of osteogenesis and hematopoiesis but also to fracture healing and disease processes. Mesenchymal stromal cells from bone (BMSCs) represent a heterogenous mixture of different subpopulations with distinct molecular and functional properties. The lineage relationship between BMSC subsets and their regulation by intrinsic and extrinsic factors are not well understood. Here,...

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PMID: 34260921
DOI: 10.1016/j.celrep.2021.109352

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