Origin and Characterization of Multipotential Mesenchymal Stem Cells Derived from Adult Human Trabecular Bone

Abstract excerpt

Much of the knowledge regarding the regulatory pathways for adult stem cell self-renewal and differentiation has been obtained from the results of in vitro cultures. However, it is unclear if adult stem cells are controlled in the same way under physiological conditions. We examined this issue with respect to the migration of stem cells to tissue injury and how switch from a migratory state to one of...