Genetic variants that affect platelet function.

doi:10.1097/MOH.0b013e3283567526

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Article

Genetic variants that affect platelet function.

Current opinion in hematology - 1 Sept 2012

Kunicki Thomas J, Williams Shirley A, Nugent Diane J

Abstract excerpt

PURPOSE OF REVIEW: This review summarizes our current knowledge of common gene variants (polymorphisms) that have small individual effects on platelet function in humans, but can cumulatively lead to hyperreactive platelets and increase risk for negative outcomes in thrombotic disorders. RECENT FINDINGS: Candidate gene association and genome-wide association studies (GWAS) have identified loci that include single...

Topics

Blood Platelets
Genetic Association Studies
Genome-Wide Association Study
Humans
Platelet Count
Platelet Function Tests
Polymorphism, Single Nucleotide
Receptors, Cell Surface
Thrombosis

Source

Open in PubMed

Identifiers

PMID: 22872156
DOI: 10.1097/MOH.0b013e3283567526

Genes

ITGA2
PEAR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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