Article
Monitoring of HIV type 1 DNA load and drug resistance in peripheral blood mononuclear cells during suppressive antiretroviral therapy does not predict virologic failure.
AIDS research and human retroviruses - 1 Aug 2012
Beck Ingrid A, Jang Minyoung, McKernan-Mullin Jennifer, Bull Marta, Wagner Thor, Huang Sharon, Song Lin-Ye, Nachman Sharon, Krogstad Paul, Eshleman Susan H, Wiznia Andrew, Frenkel Lisa M
Abstract excerpt
Our objective was to determine whether monitoring HIV-1 DNA concentration or new resistance mutations in peripheral blood mononuclear cells (PBMCs) during effective antiretroviral therapy (ART) predicts virologic failure. A retrospective analysis used blood specimens and clinical data from three nevirapine containing arms of a four-arm, open-label, randomized trial comparing ART regimens in HIV-1-infected...
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