Article
Predictors of virologic failure and genotypic resistance mutation patterns in thai children receiving non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy.
The Pediatric infectious disease journal - 1 Sept 2009
Jittamala Podjanee, Puthanakit Thanyawee, Chaiinseeard Sukrapee, Sirisanthana Virat
Abstract excerpt
BACKGROUND: Nonnucleoside reverse transcription inhibitor (NNRTI)-based antiretroviral therapy (ART) has been widely used as a first-line regimen for the treatment of HIV. This study aimed to determine the rate and predictors of virologic failure and describe patterns of resistance mutation. METHODS: The inclusion criteria were children who were <18 years and receiving NNRTI-based ART. Plasma HIV-1 RNA and CD4...
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