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Article

Neddylation and CAND1 independently stimulate SCF ubiquitin ligase activity in Candida albicans.

Eukaryotic cell - 1 Jan 2012

Sela Nadine, Atir-Lande Avigail, Kornitzer Daniel

Abstract excerpt

SCF (Skp1-cullin/Cdc53-F-box protein) ubiquitin ligases bind substrates via the variable F-box protein and, in conjunction with the RING domain protein Rbx1 and the ubiquitin-conjugating enzyme Ubc3/Cdc34, catalyze substrate ubiquitination. The cullin subunit can be modified covalently by conjugation of the ubiquitin-like protein Rub1/NEDD8 (neddylation) or bound noncovalently by the protein CAND1...

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Source

Open in PubMed Open full text

Identifiers

PMID: 22080453
DOI: 10.1128/EC.05250-11
PMCID: PMC3255936

Genes

CAND1
NEDD8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Neddylation and CAND1 independently stimulate SCF ubiquitin ligase activity in Candida albicans.PMID 22080453Read ↗

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